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  • Exposure Science Digests
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MTBE: A poster child for exposure assessment as central to effective TSCA reform

Abstract

Advanced exposure assessment is vital to improving the Toxic Substances Control Act.

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References

  1. Belpoggi F ., Soffritti M ., Filippini F ., and Maltoni C . Results of long-term experimental studies on the carcinogenicity of methyl tert-butyl ether. Ann NY Acad Sci 1997: 837: 77–95.

    Article  CAS  Google Scholar 

  2. Bird M.G ., Burleigh-Flayer H.D ., Chun J.S ., Douglas J.F ., Kneiss J.J ., and Andrews L.S . Oncogenicity studies of inhaled methyl tertiary-butyl ether (MTBE) in CD-1 mice and F-344 rats. J Appl Toxicol 1997: 17(Suppl 1): S45–S55.

    Article  Google Scholar 

  3. Davis J. M ., and Farl W.H . The paradoxes of MTBE. Toxicol Sci 2001: 61: 211–217.

    Article  CAS  Google Scholar 

  4. Erdal S ., and Goldstein B.D . Methyl tert-butyl ether as a gasoline oxygenate: lessons for environmental public policy. Annu Rev Energy Environ 2000: 25: 765–802.

  5. Fiedler N ., Kelly-McNeil K ., Mohr S ., Lehrer P ., Opiekun R.E ., Lee C . et al. Controlled human exposure to methyl tertiary butyl ether in gasoline: symptoms, psychophysiologic and neurobehavioral responses of self-reported sensitive persons. Environ Health Perspect 2000: 108: 753–763.

    Article  CAS  Google Scholar 

  6. Renn O ., and Elliott D.D . Chemicals regulation. In: Wiener J.B., Rogers M.D., Hammitt J.K., and Sand P.H. (eds). The Reality of Precaution: Comparing Risk Regulation in the United States and Europe. RFF Press: Washington, DC, 2010..

  7. Williams E.S ., Panko J ., and Paustenbach D.J . The European Union’s REACH regulation: a review of its history and requirements. Cri Rev Toxicol 2009: 39: 553–557.

    Article  Google Scholar 

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Correspondence to Bernard D Goldstein.

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Goldstein, B. MTBE: A poster child for exposure assessment as central to effective TSCA reform. J Expo Sci Environ Epidemiol 20, 229–230 (2010). https://doi.org/10.1038/jes.2010.17

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