Abstract
Mixtures of drug-resistant and drug-sensitive tumour cells growing in 3-dimensional boluses in collagen gel matrix are shown to be effectively coupled so that the response of the mixture is significantly influenced by a subpopulation making up only 1% of the total cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Rights and permissions
About this article
Cite this article
Miller, F., McEachern, D. & Miller, B. Efficiency of communication between tumour cells in collagen gel cultures. Br J Cancer 62, 360–363 (1990). https://doi.org/10.1038/bjc.1990.297
Issue Date:
DOI: https://doi.org/10.1038/bjc.1990.297
This article is cited by
-
Clonal diversity in carcinomas: its implications for tumour progression and the contribution made to it by epithelial-mesenchymal transitions
Clinical & Experimental Metastasis (2008)