Abstract
Hyperplastic and neoplastic lesions of the liver occurring “spontaneously” in C3H × Y male mice were transplanted autologously and isologously. Hyperplastic lesions did not survive in the same animal or in other animals of the same strain. Carcinomas grew in the host or in isologous mice and killed the animals. Most of the lesions were hyperplastic, and few were carcinomas. It is concluded that the histologic pattern of hyperplastic and neoplastic lesions can be correlated with the results obtained on transplantation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Rights and permissions
About this article
Cite this article
Reuber, M. Morphologic and Biologic Correlation of Hyperplastic and Neoplastic Hepatic Lesions Occurring “Spontaneously” in C3H × Y Hybrid Mice. Br J Cancer 25, 538–543 (1971). https://doi.org/10.1038/bjc.1971.69
Issue Date:
DOI: https://doi.org/10.1038/bjc.1971.69
This article is cited by
-
Histogenese und Cytogenese von Cholangiofibromen und Cholangiocarcinomen bei Nitrosomorpholin-vergifteten Ratten
Zeitschrift f�r Krebsforschung und Klinische Onkologie (1976)
-
Liver tumours in CF-1 mice exposed for limited periods to technical DDT
Zeitschrift f�r Krebsforschung und Klinische Onkologie (1974)
