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Molecular biology

Concealed enzyme coordination

Coordination between subunits is crucial for the proper functioning of multi-component molecular machines. A single-molecule study now allows glimpses into the mechanism used by subunits of one such machine.

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Figure 1: Proposed coordination mechanisms of ring ATPases.
Figure 2: Analysis of DNA translocation by the bacteriophage φ29 motor.

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Abbondanzieri, E., Zhuang, X. Concealed enzyme coordination. Nature 457, 392–393 (2009). https://doi.org/10.1038/457392a

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