Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Proteomics

Protein complexes take the bait

Many cellular functions are carried out by proteins that are bound together in complexes. In two new large-scale studies, labelled proteins are used as 'bait' to capture and identify those complexes.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Analysing protein interactions.

References

  1. Gavin, A.-C. et al. Nature 415, 141–147 (2002).

    Article  ADS  CAS  Google Scholar 

  2. Ho, Y. et al. Nature 415, 180–183 (2002).

    Article  ADS  CAS  Google Scholar 

  3. Uetz, P. et al. Nature 403, 623–627 (2000).

    Article  ADS  CAS  Google Scholar 

  4. Ito, T. et al. Proc. Natl Acad. Sci. USA 98, 4569–4574 (2001).

    Article  ADS  CAS  Google Scholar 

  5. Zhu, H. et al. Science 293, 2101–2105 (2001).

    Article  ADS  CAS  Google Scholar 

  6. Gelperin, D. et al. Proc. Natl Acad. Sci. USA 92, 11539–11543 (1995).

    Article  ADS  CAS  Google Scholar 

  7. Roberts, R. L. et al. Cell 89, 1055–1065 (1997).

    Article  CAS  Google Scholar 

  8. Beck, T. & Hall, M. N. Nature 402, 689–692 (1999).

    Article  ADS  CAS  Google Scholar 

  9. Guzder, S. N., Sung, P., Prakash, L. & Prakash, S. J. Biol. Chem. 273, 31541–31546 (1998).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kumar, A., Snyder, M. Protein complexes take the bait. Nature 415, 123–124 (2002). https://doi.org/10.1038/415123a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/415123a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing