insight
Nature 414, 92-97 (1 November 2001) | doi:10.1038/35102154
The end of the beginning for pluripotent stem cells
Peter J. Donovan1 and John Gearhart2
Abstract
Pluripotent stem cells can be expanded seemingly indefinitely in culture, maintain a normal karyotype and have the potential to generate any cell type in the body. As such they represent an incredible resource for the repair of diseased or damaged tissues in our bodies. These cells also promise to open a new window into the embryonic development of our species.
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Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
(e-mail: Email: pdonovan@lac.jci.tju.edu -
The Institute of Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
(e-mail: Email: gearhart@jhmi.edu)