Review
Nature Reviews Molecular Cell Biology 2, 599-609 (August 2001) | doi:10.1038/35085068
Transcriptional regulation by the phosphorylation-dependent factor CREB
Bernhard Mayr1 & Marc Montminy 1,2 About the authors
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Abstract
The transcription factor CREB ? for 'cyclic AMP response element-binding protein' ? functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?
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Author affiliations
- Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
- Email: montminy@salk.edu