Protein kinases play an integral role in the regulation of virtually every major cellular and developmental process, and an understanding of how protein kinases function in vivo is therefore of central importance to cell biology. Newly developed protein-kinase inhibitors provide powerful tools for understanding the functions of kinases in vivo.
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Kellogg, D. Chemical genetics: new tools for understanding signalling networks. Nat Cell Biol 2, E180–E181 (2000). https://doi.org/10.1038/35036430
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DOI: https://doi.org/10.1038/35036430
