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The fascinating life of hematopoietic stem cells

Nature Medicine volume 4, pages 1118–1119 (1998)Cite this article

Abstract

Elucidation of stem cell biology and of the unique gene products that promote stem cell self renewal and differentiation should lead to improvements in stem cell transplantation.

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Figure 1: Hematopoiesis originates on day 7 in the yolk sac (YS) blood islands perhaps generated by a precursor cell with the potential to give rise to both the endothelial and hematopoietic lineages.
Figure 2: Pluripotent hematopoietic stem cells (HSC) are ideal targets for retrovirus-mediated gene transfer.

Notes

  1. *The Second International Workshop on Hematopoietic Stem Cells, Meersburg, Germany. July 1–4, 1998. Sponsored by Amgen and Kirin Pharmaceuticals.

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Authors and Affiliations

  1. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, 21287-8967 , Maryland, USA

    Saul Sharkis

  2. Medizinische Klinik und Poliklinik, Universitätsklinikum Tübingen, Tübingen, Germany

    Lothar Kanz

  3. Hematopoiesis Section, NHGRI, NIH, Bethesda , 20892-4442, Maryland, USA

    Wolfram Brugger & Donald Orlic

Authors
  1. Saul Sharkis
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  2. Lothar Kanz
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  3. Wolfram Brugger
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  4. Donald Orlic
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Sharkis, S., Kanz, L., Brugger, W. et al. The fascinating life of hematopoietic stem cells. Nat Med 4, 1118–1119 (1998). https://doi.org/10.1038/2611

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