Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Lethal Effect of Near-ultraviolet Irradiation on Mammalian Cells in Culture

Abstract

THE lethal and mutagenic effects of ultraviolet light of wavelength below 300 nm on bacterial and mammalian cells have been the subject of many research projects, and several laboratories are investigating the action of near-ultraviolet irradiation provided by black light (300 to 420 nm) on bacterial cells1. There are, however, only a few studies on the effect of black light (near-ultraviolet) on mammalian cells2,3. Several laboratories have reported effects of both visible fluorescent light, which does produce a significant amount of emission in the near-ultraviolet region, and black light on mammalian cells after the incorporation of bromodeoxyuridine (BUdR) into the cell nucleic acid3–7.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Eisenstark, A., Adv. Genet., 16, 167 (1971).

    Article  CAS  Google Scholar 

  2. Klein, R. M., Photochem. Photobiol., 6, 841 (1967).

    Article  CAS  Google Scholar 

  3. Chu, E. H. Y., Sun, N. C., and Chang, C., Proc. natn. Acad. Sci. U.S.A., 69, 3459 (1972).

    Article  ADS  CAS  Google Scholar 

  4. Puck, T. T., and Kao, F. T., Proc. natn. Acad. Sci. U.S.A., 58, 1227 (1967).

    Article  ADS  CAS  Google Scholar 

  5. Yang, S. J., and Hahn, G. M., Photochem. Photobiol., 11, 131 (1970).

    Article  CAS  Google Scholar 

  6. Ben-Hur, E., and Elkind, M. M., Mutation Res., 14, 237 (1972).

    Article  CAS  Google Scholar 

  7. Fogel, Marian, Nature new Biol., 241, 182 (1973).

    Article  CAS  Google Scholar 

  8. Todaro, G. J., and Green, H., J. cell Biol., 17, 299 (1963).

    Article  CAS  Google Scholar 

  9. Shipley, W. V., Elkind, M. M., and Prather, W. B., Radial. Res., 47, 437 (1971).

    Article  ADS  CAS  Google Scholar 

  10. Szybalski, W., Szybalska, E. H., and Ragni, G., Nat. Cancer Inst. Monogr., 7, 75 (1962).

    Google Scholar 

  11. Dulbecco, R., and Freeman, G., Virology, 8, 396 (1959).

    Article  CAS  Google Scholar 

  12. Black Light (General Electric Publication TP-125, 1969).

  13. Webb, R. B., and Lorenz, J., J. Bact., 112, 649 (1972).

    CAS  PubMed  Google Scholar 

  14. Ferron, W. L., Eisenstark, A., and Mackay, D., Biochim. biophys. Acta, 277, 651 (1972).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

WANG, R., STOIEN, J. & LANDA, F. Lethal Effect of Near-ultraviolet Irradiation on Mammalian Cells in Culture. Nature 247, 43–45 (1974). https://doi.org/10.1038/247043a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/247043a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing