Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Mutants of the Visual Pathway of Drosophila melanogaster

Nature volume 227, pages 518–520 (1970)Cite this article

Abstract

WITH the objective of analysing visual processes, we have attempted to generate mutants of Drosophila melanogaster with single-step lesions on the genes controlling the visual pathway1. One of these (x-7) had an abnormal electroretinogram (ERG) consisting apparently of responses from the photoreceptor layer alone. Similar ERGs could be obtained from the mutants tan1,2 and ebony2. Indeed, the mutants x-7 and tan seemed to be allelic1. We now have new mutants, and ERG characteristics suggest genetic blocks in the visual pathway of several of them.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Pak, W. L., Grossfield, J., and White, N. V., Nature, 222, 351 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Hotta, Y., and Benzer, S., Nature, 222, 354 (1969).

    Article  ADS  CAS  Google Scholar 

  3. Lewis, E. B., and Bacher, F., Drosophila Inform. Serv., 43, 193 (1968).

    Google Scholar 

  4. Lindsley, D. L., and Grell, E. H., Genetic Variations of Drosophila melanogaster, Carnegie Institution of Washington, Pub. No. 627 (1968).

    Google Scholar 

  5. Goldsmith, T. H., and Fernandez, H. R., J. Exp. Biol., 49, 669 (1968).

    CAS  PubMed  Google Scholar 

  6. Burkhardt, D., in Symp. Soc. Exp. Biol., 16 (Academic Press, New York, 1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biological Sciences, Purdue University, Lafayette, Indiana, 47907

    WILLIAM L. PAK, JOSEPH GROSSFIELD & KAY S. ARNOLD

Authors
  1. WILLIAM L. PAK
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. JOSEPH GROSSFIELD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. KAY S. ARNOLD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

PAK, W., GROSSFIELD, J. & ARNOLD, K. Mutants of the Visual Pathway of Drosophila melanogaster. Nature 227, 518–520 (1970). https://doi.org/10.1038/227518b0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/227518b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing