Abstract
THE finding that allogeneic pig liver transplants frequently survive for a significantly prolonged period of time even without immunosuppression has led to a new line of research1,2. Calne and his colleagues have shown that the recipient of an allogeneic liver transplant showed partial tolerance towards kidney, and to a lesser extent towards skin transplants, when these were obtained from the same animal as was the liver.
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References
Peacock, J. H., and Terblanche, J., The Liver, 333 (Butterworths, London, 1967).
Calne, R. Y., White, H. J. O., Yoffa, D. E., Maginn, R. R., Binns, R. M., Samuel, J. R., and Mollna, V. P., Brit. Med. J., 2, 478 (1967).
Calne, R. Y., Sells, R. A., Pena, J. R., Davis, D. R., Millard, P. R., Herbertson, B. M., Binns, R. M., and Davies, D. A., Nature, 223, 472 (1969).
Kissmeyer-Nielsen, F., and Kjerbye, K. E., Histocompatibility Testing, 381 (Munksgaard, Copenhagen, 1967).
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VAN ROOD, J., VAN LEEUWEN, A. & VAN SANTEN, M. Anti HL-A2 Inhibitor in Normal Human Serum. Nature 226, 366–367 (1970). https://doi.org/10.1038/226366a0
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DOI: https://doi.org/10.1038/226366a0