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Albumin Syracuse: a Variant demonstrated at Acid pH

Abstract

ELECTROPHORETIC variants of human albumin seem to be quite rare. Screening for albumin heterogeneity has been carried out conventionally at alkaline pH, usually 8.6. Several studies of different animal species suggest that additional albumin variants could be identified by electrophoresis at acid pH1–3. To test this hypothesis it was decided to screen sera by electrophoresis in acid buffers.

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SCHNEIDERMAN, H., BERGER, J. & KRIEG, A. Albumin Syracuse: a Variant demonstrated at Acid pH. Nature 218, 1159–1160 (1968). https://doi.org/10.1038/2181159a0

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