Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Two Point Discrimination of Subcortical Electrical Stimulation

Abstract

LOUCKS first showed that electrical stimulation of the cerebral cortical surface could serve as a conditioned stimulus in a behavioural situation1. A number of workers have been concerned with this issue since the original findings2–4. It is now well established that stimulation of subcortical as well as cortical sites can serve as conditioned stimuli. Of particular interest is the fact that when a stimulus has been established, very limited primary generalization to brain sites other than the conditioned site occurs5. For example, if a stimulus applied to the head of the caudate nucleus is used as the conditioned stimulus, generalization is found only in homotopic contralateral caudate sites and in nearby points in the same structure4.

This is a preview of subscription content, access via your institution

Access options

Similar content being viewed by others

References

  1. Loucks, R. B., J. Comp. Psychol., 16, 439 (1933).

    Article  Google Scholar 

  2. Doty, R. W., and Rutledge, L. T., J. Neurophysiol., 428 (1959).

  3. Nielson, H. C., Doty, R. W., and Rutledge, L. T., Amer. J. Physiol., 194, 427 (1958).

    CAS  PubMed  Google Scholar 

  4. Buchwald, N. A., Romero-Sierra, C., Hull, C. D. and Wakefield, C., Exp. Neurology, 17, 451 (1967).

    Article  CAS  Google Scholar 

  5. Doty, R. W., J. Neurophysiol., 28, 623 (1965).

    Article  CAS  Google Scholar 

  6. Morrell, F., Epilepsia, 1, 538 (1960).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ROMERO-SIERRA, C., BUCHWALD, N., WAKEFIELD, C. et al. Two Point Discrimination of Subcortical Electrical Stimulation. Nature 214, 837–838 (1967). https://doi.org/10.1038/214837a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/214837a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing