Abstract
CONSIDERABLE interest has developed in the germ-free animal as an assay system for potential oncogenic viruses. Theoretically it should provide a more uniform test system than the conventional animal with its unpredictable microflora which may influence unpredictably the response to the agent being studied. For this reason we undertook a comparative study of Friend virus infection in germ-free and conventional mice of the same strain. This communication concerns the results of this investigation.
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References
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MIRAND, E., GRACE, J. Responses of Germ-free Mice to Friend Virus. Nature 200, 92–93 (1963). https://doi.org/10.1038/200092a0
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DOI: https://doi.org/10.1038/200092a0
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