Abstract
RECENTLY it has been reported, by Ciba Laboratories1,2, that two reserpine analogues show more specific effects than reserpine. Methyl-18-O(3-NN-dimethylaminobenzoyl)reserpate (or SU 5171) exhibits sedative activity, while carbethoxysyringoyl-methylreserpate (syrosingopine or SU 3118) is effective in decreasing blood tension (see formulæ).
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References
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GARATTINI, S., MORTARI, A., VALSECCHI, A. et al. Reserpine Derivatives with Specific Hypotensive or Sedative Activity. Nature 183, 1273–1274 (1959). https://doi.org/10.1038/1831273a0
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DOI: https://doi.org/10.1038/1831273a0
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