Abstract
IT is not yet known for certain whether the physiological responses to bee venom include the formation of antibodies. Earlier investigators have obtained divergent results when investigating immunization against different effects of the venom. This is probably in part due to the fact that a series of pharmacological and enzymatic reactions are caused by quite different constituents of the venom1. In recent years, several proteins with various biological properties have been isolated: first, the pharmacologically highly active toxin-fraction (so-called ‘fraction I’)2 ; then the enzymes phospholipase A 3 and hyaluronidase4, which on electrophoresis migrate in the so-called ‘fraction II’. From these findings arises the question whether antigenic properties may be found with these substances.
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HABERMANN, E., EL KAREMI, M. Antibody Formation by Protein Components of Bee Venom. Nature 178, 1349 (1956). https://doi.org/10.1038/1781349a0
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DOI: https://doi.org/10.1038/1781349a0
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