Abstract
Our understanding of tolerance mechanisms has progressed to the point that tolerance-induction protocols are being tested in humans for organ transplantation. However, a range of scientific, ethical, logistic and commercial issues have arisen, and must be resolved before tolerance induction for human allograft patients can become a reality.
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Waldmann, H. Transplantation tolerance—where do we stand?. Nat Med 5, 1245–1248 (1999). https://doi.org/10.1038/15197
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DOI: https://doi.org/10.1038/15197
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