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The skinny on neurotrophins

Brain-derived neurotrophic factor (BDNF) is best known as a regulator of brain development and plasticity. New evidence suggests that BDNF is also a component of the hypothalamic melanocortin pathway that controls body weight in adults.

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Figure 1: Schematic of the mediobasal hypothalamus.

Erin Boyle

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Correspondence to Michael W Schwartz.

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Wisse, B., Schwartz, M. The skinny on neurotrophins. Nat Neurosci 6, 655–656 (2003). https://doi.org/10.1038/nn0703-655

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