Abstract
Objective:
In our laboratory, a decrease in fetal lung maturity (FLM) testing on amniotic fluid occurred over a 10-year period, and we desired to determine if this was a national phenomenon and, if present, ascertain possible etiologies.
Study Design:
Society of Maternal–Fetal Medicine fellows, both in academic centers and private practice, were surveyed with regard to current usage of FLM testing.
Result:
Of 680 surveys, 417 (61%) responses were returned and 60% noted a decrease in FLM testing (range of reduction—foam stability index 65%, fluorescence polarization 35%, phosphatidyl glycerol 71%, lecithin/sphingomyelin ratio 70%). The most common reason suggested for the decline is that the tests were not needed for patient management.
Conclusion:
Obstetric patterns of FLM testing have declined, principally in near-term pregnancies, and this could adversely affect neonatal outcome.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Goldenberg RL, Rouse DJ . Prevention of premature birth. N Engl J Med 1998; 339: 313–320.
Crowley PA . Antenatal corticosteroid therapy: a meta-analysis of the randomized trials. 1972–94. Am J Obstet Gynecol 1995; 173: 322–335.
Ferrara TB, Hoekstra RE, Couser RJ . Effects of surfactant therapy on outcome of infants with birth weights of 600–750 grams. Clinical and laboratory observations. J Pediatr 1991; 119: 455–466.
Wegmen ME . Annual summary of vital statistics—1992. Pediatrics 1993; 92 (6): 743–754.
Arias E, MacDorman MF, MocDorman MF, Strobino DM, Guyer B . Annual summary of vital statistics–2002. Pediatrics 2003; 112 (6): 1215–1230.
Jones JS, Istwan NB, Jacques D, Coleman SK . Is 34 weeks an acceptable goal for a complicated singleton pregnancy? Am J Manag Care 2002; 42–47.
Myers ER, Alverez JG, Richardson DK, Ludmir J . Cost-effectiveness of fetal lung maturity testing in preterm labor. Obstet Gynecol 1997; 90: 824–829.
Ghidini A, Locatelli A . Indices of maturity. Contemp Ob Gyn 2007; 66: 55–66.
American College of Obstetricians and Gynecologists. Assessment of Fetal Lung Maturity. ACOG Educational Bulletin 23. ACOG: Washington, DC, 1996.
American College of Obstetric and Gynecology. Induction of labor. ACOG technical bulletin no. 10. ACOG: Washington, DC, 1999.
Amon S, Dolfin T, Litmanovitz I, Regev R, Bauer S, Fejgin M . Preterm labour at 34–36 weeks of gestation: should it be arrested? Pediatr Perinat Epidemiol 2001; 15: 252–256.
Elliott JP, Istwan NB, Colliins A, Rhea DJ, Stanziano GJ . Indicated and non-indicated preterm delivery in twin gestations: impact on neonatal outcome and cost. J Perinat 2005; 25: 4–7.
Elliott JP, Istwan NB, Jacques DL, Coleman SK, Stanziano GJ . Consequences of non-indicated preterm delivery in singleton gestations. J Reprod Med 2003; 48 (9): 713–717.
Raju TN, Higgins RD, Stark AR, Loveno KJ . Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics 2006; 118 (3): 1207–1213.
Acknowledgements
This study had no funding source.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
McGinnis, K., Brown, J. & Morrison, J. Changing patterns of fetal lung maturity testing. J Perinatol 28, 20–23 (2008). https://doi.org/10.1038/sj.jp.7211880
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.jp.7211880
Keywords
This article is cited by
-
Systems biology evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity
BMC Medical Genomics (2015)
-
Hospitalized late preterm mild preeclamptic patients with mature lung testing: what are the risks of delivery?
Journal of Perinatology (2009)