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Noncoding RNAs at the membrane

Nature Structural & Molecular Biology volume 12, pages 285–286 (2005)Cite this article

A noncoding regulatory RNA in Escherichia coli, SgrS, downregulates the message for the glucose transporter, limiting accumulation of toxic sugar phosphates. Now a new study finds that SgrS can work only when the target message is brought to the membrane by transmembrane coding regions.

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Figure 1: SgrS targets the ptsG message only at the membrane.

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Acknowledgements

We thank G. Storz, D. Fitzgerald, M. Guillier and H. Bernstein for their comments on the manuscript. C.K.V. is supported by a postdoctoral fellowship from the American Cancer Society.

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  1. Laboratory of Molecular Biology, National Cancer Institute, Bethesda, 20892, Maryland, USA

    Carin K Vanderpool & Susan Gottesman

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  1. Carin K Vanderpool
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  2. Susan Gottesman
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Vanderpool, C., Gottesman, S. Noncoding RNAs at the membrane. Nat Struct Mol Biol 12, 285–286 (2005). https://doi.org/10.1038/nsmb0405-285

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