Much attention has focused on the increasing prevalence of childhood type 2 diabetes mellitus. However, considerable evidence suggests that the incidence of childhood type 1 diabetes mellitus is also increasing. The results of a multicenter registration study from Europe confirm this alarming trend, which has important health-care implications.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
Clinical Proteomics Open Access 15 October 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Harjutsalo, V., Sjöberg, L. & Tuomilehto, J. Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study. Lancet 371, 1777–1782 (2008).
Patterson, C. C. et al. Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study. Lancet 373, 2027–2033 (2009).
Stene, L. C. et al. Birth weight and childhood onset type 1 diabetes: population based cohort study. BMJ 322, 889–892 (2001).
Wilkin, T. J. The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia 44, 914–922 (2001).
Gale, E. A. To boldly go—or to go too boldly? The accelerator hypothesis revisited. Diabetologia 50, 1571–1575 (2007).
Knai, C., Suhrcke, M. & Lobstein, T. Obesity in Eastern Europe: an overview of its health and economic implications. Econ. Hum. Biol. 5, 392–408 (2007).
Dabelea, D. The accelerating epidemic of childhood diabetes. Lancet 372, 1999–2000 (2009).
Chan, J. C. et al. Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA 301, 2129–2140 (2009).
TEDDY study group. The Environmental Determinants of Diabetes in the Young (TEDDY) study. Ann. NY Acad. Sci. 1150, 1–13 (2008).
Akerblom, H. K. et al. Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study. Diabetologia 48, 829–837 (2005).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Ma, R., Chan, J. Incidence of childhood type 1 diabetes: a worrying trend. Nat Rev Endocrinol 5, 529–530 (2009). https://doi.org/10.1038/nrendo.2009.180
Issue Date:
DOI: https://doi.org/10.1038/nrendo.2009.180
This article is cited by
-
Epidemiology of diabetes and diabetic complications in China
Diabetologia (2018)
-
N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
Clinical Proteomics (2016)
-
Prevention or acceleration of type 1 diabetes by viruses
Cellular and Molecular Life Sciences (2013)
