Abstract
Neurons in the auditory cortex can lock to the fine timing of acoustic stimuli with millisecond precision, but it is not known whether this precise spike timing can be used to guide decisions. We used chronically implanted microelectrode pairs to stimulate neurons in the rat auditory cortex directly and found that rats can exploit differences in the timing of cortical activity that are as short as 3 ms to guide decisions.
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Acknowledgements
We thank R. Eifert and B. Burbach for technical assistance, A. Kepecs and Z. Mainen for comments on the manuscript, and members of the Zador lab for helpful discussions.
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Yang, Y., DeWeese, M., Otazu, G. et al. Millisecond-scale differences in neural activity in auditory cortex can drive decisions. Nat Neurosci 11, 1262–1263 (2008). https://doi.org/10.1038/nn.2211
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DOI: https://doi.org/10.1038/nn.2211
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