Improved expansion microscopy provides a super-resolution method that is accessible to any laboratory with a fluorescence microscope.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chen, F., Tillberg, P.W. & Boyden, E.S. Science 347, 543–548 (2015).
Tillberg, P.W. et al. Nat. Biotechnol. 34, 987–992 (2016).
Ku, T. et al. Nat. Biotechnol. 34, 973–981 (2016).
Chozinski, T.J. et al. Nat. Methods 13, 485–488 (2016).
Galbraith, C.G. & Galbraith, J.A. J. Cell Sci. 124, 1607–1611 (2011).
Richardson, D.S. & Lichtman, J.W. Cell 162, 246–257 (2015).
Micheva, K.D. & Smith, S.J. Neuron 55, 25–36 (2007).
Murray, E. et al. Cell 163, 1500–1514 (2015).
Chen, F. et al. Nat. Methods 13, 679–684 (2016).
Dodt, H.U. et al. Nat. Methods 4, 331–336 (2007).
Acknowledgements
The authors thank the Neurobiology Course at the Marine Biological Laboratory for being their summer home for many years. T.M.'s laboratory is supported by the Deutsche Forschungsgemeinschaft (DFG) through the Munich Center for Systems Neurology (SyNergy; EXC 1010), the Center for Integrated Protein Science Munich (CIPSM, EXC 114), Collaborative Research Center 870, Priority Program 1710 and DFG Research Grant (MI 674/7-1). Further support came from the European Research Council under the European Union's Seventh Framework Program (FP/2007-2013; ERC Grant Agreement n. 616791) and the German-Israeli Foundation. T.M. is also associated with the German Center for Neurodegenerative Diseases (DZNE Munich). P.E. was supported by the DFG Research Training Group 1373 and the Graduate School of the Technische Universität München (TUM-GS); C.F. is supported by the Graduate School of Systemic Neuroscience (GSN, GSC 82).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Engerer, P., Fecher, C. & Misgeld, T. Super-resolution microscopy writ large. Nat Biotechnol 34, 928–930 (2016). https://doi.org/10.1038/nbt.3669
Published:
Issue Date:
DOI: https://doi.org/10.1038/nbt.3669