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Allocation of patients to treatment groups in a controlled clinical study

Abstract

In a controlled clinical study ("clinical trial") to compare 2 or more treatments for a disease, an objective method of allocating patients to treatment groups is needed. Various existing methods of allocation are described, including those which take account of patients' pre-treatment characteristics.

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White, S., Freedman, L. Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer 37, 849–857 (1978). https://doi.org/10.1038/bjc.1978.124

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  • DOI: https://doi.org/10.1038/bjc.1978.124

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