Nuclear factors must access specific sites within genomic DNA to function, yet the DNA is bundled up into many nucleosomes. Is the DNA sequence sufficiently informative to predict where each nucleosome will be?
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Richmond, T. Predictable packaging. Nature 442, 750–751 (2006). https://doi.org/10.1038/442750a
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DOI: https://doi.org/10.1038/442750a