Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro Derivatives of Dibenzo-p-dioxin

Nature volume 220, pages 702–703 (1968)Cite this article

Abstract

ONE of the toxic compounds known as hydropericardium factor (chick oedema factor) is 1,2,3,7,8,9-hexachlorodi-benzo-p-dioxin1. Because it is highly improbable that these very toxic compounds are naturally occurring components of the fats from which they have been isolated, the question of their origin has aroused speculation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Chem. Eng. News, 45, No. 5, 10 (1967).

  2. Tomita, M., Ueda, S., and Narisada, M., Yakugaku Zasshi, 79, 186 (1959); Chem. Abstr., 53, 1315d (1959).

    Article  CAS  Google Scholar 

  3. Verrett, M. J., Marliac, J., and McLaughlin, J., J. Assoc. Offic. Agr. Chemists, 47, 1003 (1964).

    CAS  Google Scholar 

  4. Neal, P., J. Assoc. Offic. Anal. Chemists, 50, 1338 (1967).

    CAS  Google Scholar 

  5. Official Methods of Analysis, 10th ed., sees. 26.087–26.091. (Association of Official Agricultural Chemists, Washington, D.C., 1965).

  6. Wootton, J. C., Artman, N. R., and Alexander, J. C., J. Assoc. Offic. Agr. Chemists, 45, 739 (1962).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Bureau of Science, Food and Drug Administration, Department of Health, Education and Welfare, Washington, DC

    G. R. HIGGINBOTHAM, ANITA HUANG, DAVID FIRESTONE, JACQUELINE VERRETT, JOHN RESS & A. D. CAMPBELL

Authors
  1. G. R. HIGGINBOTHAM
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. ANITA HUANG
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. DAVID FIRESTONE
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. JACQUELINE VERRETT
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. JOHN RESS
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. D. CAMPBELL
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

HIGGINBOTHAM, G., HUANG, A., FIRESTONE, D. et al. Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro Derivatives of Dibenzo-p-dioxin. Nature 220, 702–703 (1968). https://doi.org/10.1038/220702a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/220702a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing