Abstract
THE presence of an enzyme at the surface of influenza virus was first suggested by Hirst1. Burnet and co-workers2 have presented much evidence to substantiate Hirst's assumption, especially by their discovery that the ability of certain mucoproteins to act as competitive inhibitors for hæmagglutination by heated influenza B virus3 is lost after pre-treatment of the mucoids with active virus. Serum mucoprotein, ovarian cyst mucoid, blood group substances A and O, gonadotrophic hormone proved to be inhibitors of hæmagglutination by heated virus and substrates for active virus.
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References
Hirst, G. K., J. Exp. Med., 76, 195 (1942).
Burnet, F. M., et al., Aust. J. Exp. Biol. and Med. Sci., 26, 403 (1948)
Francis, T., J. Exp. Med., 85, 1 (1947).
Gottschalk, A., and Lind, P. E., Brit. J. Exp. Path., 30, 85 (1949).
Fazekas de St. Groth, S., and Gottschalk, A. (in preparation).
French, E. L., unpublished (1948).
Stone, J. D., Aust. J. Exp. Biol. and Med. Sci. (in the press).
Morgan, W. T. J., and Elson, L. A., Biochem. J., 28, 988 (1934).
Elson, L. A., and Morgan, W. T. J., Biochem. J., 27, 1824 (1933).
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GOTTSCHALK, A., LIND, P. Product of Interaction between Influenza Virus Enzyme and Ovomucin. Nature 164, 232–233 (1949). https://doi.org/10.1038/164232a0
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DOI: https://doi.org/10.1038/164232a0
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