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Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution

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Abstract

A simple and versatile treatment was developed to provide various metallic biomaterials such as Ti, NiTi, Ta and SUS 316L stainless steel with in vitro bioactivity or ability to deposit carbonate-incorporated apatite in a simulated body fluid (Kokubo solution). A well-crystallized anatase layer deposited on the metallic biomaterials surfaces after soaking them at 60 °C for 24 h in an aqueous solution of titanium tetrafluoride (40 mM) whose pH was adjusted to 1.9 with HCl. The as-coated anatase layers did not deposit apatite. When heated at 300 °C they were so bioactive as to deposit apatite within 5 day(s) in the Kokubo solution. The trace amount of fluorine weakly bound in the as-coated anatase layers was suggested to be one of the factors that suppressed the bioactivity.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, Zhejiang University, Hangzhou, 310027, People's, Republic of China

    Jin-Ming Wu

  2. Biomaterials Laboratory, Faculty of Engineering, Okayama University, Tsushima, Okayama-shi, 700-8530, Japan

    Fan Xiao, Satoshi Hayakawa, Kanji Tsuru, Shinji Takemoto & Akiyoshi Osaka

Authors
  1. Jin-Ming Wu
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  2. Fan Xiao
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  3. Satoshi Hayakawa
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  4. Kanji Tsuru
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  5. Shinji Takemoto
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  6. Akiyoshi Osaka
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Correspondence to Satoshi Hayakawa.

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Wu, JM., Xiao, F., Hayakawa, S. et al. Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution. Journal of Materials Science: Materials in Medicine 14, 1027–1032 (2003). https://doi.org/10.1023/B:JMSM.0000003998.37583.d7

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  • DOI: https://doi.org/10.1023/B:JMSM.0000003998.37583.d7

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