Abstract
Electron microscopy showed that whole-body γ-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of γ-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.
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Popuchiev, V.V., Yakovleva, N.D., Konoplyannikov, A.G. et al. Ultrastructure of the Pineal Gland after γ-Irradiation under Conditions of Inhibition of Adrenocortical Function. Bulletin of Experimental Biology and Medicine 135, 603–607 (2003). https://doi.org/10.1023/A:1025402007545
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DOI: https://doi.org/10.1023/A:1025402007545