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CASE REPORT: Use of Activated Recombinant Human Factor VII (rhFVIIa) for Colonic Polypectomies in Patients with Cirrhosis and Coagulopathy

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References

  1. Craxi A, Camma C, Giunta M: Clinical aspects of bleeding complications in cirrhotic patients. Blood Coagul Fibrinolysis 11:S75-S79, 2000

    Google Scholar 

  2. Poles MA, Martin P: Routine endoscopy in liver transplant candidates: is it indicated? Am J Gastroenterol 94(4):871-872, 1999

    Google Scholar 

  3. McGuire B: Safety of endoscopy in patients with end-stage liver disease. Gastrointest Endosc Clin North Am 11:111-130, 2001

    Google Scholar 

  4. Naveau S, Chaput JC, Bedossa P, Poynard T, Pauphilet C, Ink O, Houdayer C, Aubert A: Cirrhosis as an independent risk factor for colonic adenomas. Gut 33(4):535-540, 1992

    Google Scholar 

  5. Bardou M, Montembault S, Giraud V, Balian A, Borotto E, Houdayer C, Capron F, Chaput JC, Naveau S: Excessive alcohol consumption favours high risk polyp or colorectal cancer occurrence among patients with adenomas: a case control study. Gut J 50(1):38-42, 2002

    Google Scholar 

  6. Rabinovitz M, Schade RR, Dindzans VJ, Belle SH, Van Thiel DH, Gavaler JS: Colonic disease in cirrhosis. An endoscopic evaluation in 412 patients. Gastroenterology 99(1):195-199, 1990

    Google Scholar 

  7. Scandalis N, Archimandritis A, Kastanas K, Spiliadis C, Delis B, Manika Z: Colonic findings in cirrhotics with portal hypertension. A prospective colonoscopic and histological study. J Clin Gastroenterol 18(4):325-328, 1994

    Google Scholar 

  8. Bresci G, Gambardella L, Parisi G, Federici G, Bertini M, Rindi G, Metrangolo S, Tumino E, Bertoni M, Cagno MC, Capria A: Colonic disease in cirrhotic patients with portal hypertension: an endoscopic and clinical evaluation. J Clin Gastroenterol 26(3):222-227, 1998

    Google Scholar 

  9. Zaman A, Hapke R, Flora K, Rosen H, Benner K: Prevalence of upper and lower gastrointestinal tract findings in liver transplant candidates undergoing screening endoscopic evaluation. Am J Gastroenterol 94(4):895-899, 1999

    Google Scholar 

  10. Rosen L, Bub DS, Reed JF, Nastasee SA: Hemorrhage following colonoscopic polypectomy. Dis Colon Rectum 36:1126-1131, 1993

    Google Scholar 

  11. Gibbs DH, Opelka FG, Beck DE, Hicks TC, Timmcke AE, Gathright JB Jr: Postpolypectomy colonic hemorrhage. Dis Colon Rectum J 39(7):806-810, 1996

    Google Scholar 

  12. Nahas SC, Alves PR, Borba MR, Nahas CS, Sobrado Junior CW, Araujo SE, Bringel RW, Lourencao JL, Habr-Gama A: Polypectomies: colonic endoscopic resections. Arq Gastroenterol J 36(3):133-138, 1999

    Google Scholar 

  13. Webb WA, McDaniel L, Jones L: Experience with 1000 colonoscopic polypectomies. Ann Surg M 201(5):626-632, 1985

    Google Scholar 

  14. Johnson JF: Procedure-specific outcomes assessment for colonoscopy. Gastrointest Endosc Clin North Am 9:625-637, 1999

    Google Scholar 

  15. Mammen EF: Coagulation defects in liver disease. Med Clin of North Am 78(3):545-554, 1994

    Google Scholar 

  16. Hedner U: Novoseven as a universal haemostatic agent. Blood Coagul Fibrinolysis 11:S107-S111, 2000

    Google Scholar 

  17. American Society for Gastrointestinal Endoscopy: Guideline on the management of anticoagulation and antiplatelet therapy for endoscopic procedures. Gastrointest Endosc 48:672-675, 1998

  18. Bernstein DE, Jeffers L, Erhardtsen E, Reddy KR, Glazer S, Squiban P, Bech R, Hedner U, Schiff ER: Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: A preliminary study. Gastroenterology 113:1930-1937, 1997

    Google Scholar 

  19. Papatheodoridis GV, Chung S, Keshav S, Pasi J, Burroughs AK: Correction of both prothrombin time and primary haemostasis by recombinant factor VII during therapeutic alcohol injection of hepatocellular cancer in liver cirrhosis. J Hepatol 31:747-750, 1999

    Google Scholar 

  20. Bernstein D: Effectiveness of the recombinant factor VIIa in patients with the coagulopathy of advanced child's B and C cirrhosis. Semin Thromb Hemost 26:437-438, 2000

    Google Scholar 

  21. Lindley CM, Sawyer WT, Macik G, Lusher J, Harrison JF, Baird-Cox K, Birch K, Glazer S, Roberts HR: Pharmacokinetics and pharmacodynamics of recombinant factor VIIa. Clin Pharmacol Ther 55:638-648, 1994

    Google Scholar 

  22. Monroe DM, Hoffman M, Oliver JA, Roberts HR: Platelet activity of high-dose factor VIIa is independent of tissue factor. Br J Hematol 99:542-547, 1997

    Google Scholar 

  23. Meijer K, Peters FTM, van der Meer J: Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa. Blood Coagul Fibrinolysis 12:211-213, 2001

    Google Scholar 

  24. Wilbourn B, Harrison P, Mackie I, Liesner R, Hann I, Machin S: Recombinant factor VIIa activates platelets in whole blood. Br S Haemostat Thromb 12:A6-A7, 2001 (abstract)

    Google Scholar 

  25. Thomas AE, Plews DE: Use of recombinant factor VIIa in platelet disorders—a single center experience. Br S Haemostat Thromb 12:A14-A15, 2001 (abstract)

    Google Scholar 

  26. Berntorp E, Stigendal L, Lethagen S, Olofsson L, Hedner U: Novoseven in warfarin-treated patients. Blood Coagul Fibrinolysis 11:S113-S115, 2000

    Google Scholar 

  27. Lusher J, Ingerslev J, Roberts H, Hedner U: Clinical experience with recombinant factor VIIa. Blood Coagul Fibrinolysis 9:119-128, 1998

    Google Scholar 

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Authors
  1. Abhinandana Anantharaju
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  2. Kapil Mehta
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  3. Ayse L. Mindikoglu
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  4. David H. Van Thiel
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Anantharaju, A., Mehta, K., Mindikoglu, A.L. et al. CASE REPORT: Use of Activated Recombinant Human Factor VII (rhFVIIa) for Colonic Polypectomies in Patients with Cirrhosis and Coagulopathy. Dig Dis Sci 48, 1414–1424 (2003). https://doi.org/10.1023/A:1024144217614

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