Abstract
Almost all alveolar macrophages in the mouse lung were strongly immunoreactive for epidermal-type fatty acid binding protein. At the electron microscope level, the immunoreactive material was localized diffusely in the cytoplasm but not within the nucleus. A certain number of alveolar type II epithelial cells were also immunoreactive for the protein with variable immuno-intensity, while a substantial number of the type II cells were immunonegative. No immunoreactive interstitial fibroblasts were encountered. Based on the present findings, possible roles of epidermal-type fatty acid binding protein in the host-defence mechanism played by alveolar macrophages are suggested.
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Owada, Y., Abdelkawi Abdelwahab, S., Suzuki, R. et al. Localization of Epidermal-type Fatty Acid Binding Protein in Alveolar Macrophages and Some Alveolar Type II Epithelial Cells in Mouse Lung. Histochem J 33, 453–457 (2001). https://doi.org/10.1023/A:1014420330284
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DOI: https://doi.org/10.1023/A:1014420330284