Abstract
The study addressed to resolve the mechanism involved in cholesterol‐dependent regulation of giardia encystation process, revealed that (a) the trophozoites have the ability to express genes coding for receptor‐Ck and sterol element binding protein (SREBP); (b) inhibition of cholesterol dependent activation of receptor‐Ck results in the upregulation of CWP‐1 gene expression leading to encystation process. Based upon these findings, we propose that receptor‐Ck dependent signalling is responsible for the regulation of giardia encystation process by cholesterol.
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References
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Kaul, D., Rani, R. & Sehgal, R. Receptor‐Ck regulates giardia encystation process. Mol Cell Biochem 225, 167–169 (2001). https://doi.org/10.1023/A:1012277001794
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DOI: https://doi.org/10.1023/A:1012277001794