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Transient Global Amnesia (TGA) in an MEG Study

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Abstract

A patient who had experienced an attack of transient global amnesia (TGA) was examined using neurophysiological methods. Magnetoencephalography (MEG) was performed and the Wechsler Memory Scale-Revised (WMS-R) test was administered at 5 days and at more than a month after the TGA episode. MEG data on neuronal activity obtained while the patient was undertaking a working memory task and during rest were analyzed using the wavelet-crosscorrelation method, which reveals time-lag and information flow between related sites in the brain. The WMS-R memory scores showed dramatic improvement when the test was administered a month following the attack, although no significant changes were observed in EEG, MRI and SPECT data. The MEG study revealed that under a working memory load how the neuron works functionally and the information propagates assembly within the right hemisphere, and that these brain functions were not performed adequately shortly after the TGA attack.

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Authors and Affiliations

  1. Department of Human Welfare and Department of Child Education,, Osaka Jonan Women's College,, Osaka,, Japan

    Yuko Mizuno-Matsumoto

  2. Division of Functional Diagnostic Imaging,, Osaka University Medical School,, Osaka,, Japan

    Yuko Mizuno-Matsumoto & Shinichi Tamura

  3. Department of Information Systems Engineering, Graduate School of Engineering,, Osaka University,, Osaka,, Japan

    Yuko Mizuno-Matsumoto & Susumu Date

  4. Ishijima Clinic,, Hyogo,, Japan

    Masatsugu Ishijima

  5. Department of Neuropsychiatry,, Osaka University Medical School,, Osaka,, Japan

    Kazuhiro Shinosaki, Takashi Nishikawa, Satoshi Ukai, Yoshitaka Ikejiri, Yoshitsugu Nakagawa, Ryouhei Ishii, Hiromasa Tokunaga & Masatoshi Takeda

  6. Osaka Prefectural College of Health Sciences,, Osaka,, Japan

    Tsuyoshi Inouye

  7. Cybermedia Center,, Osaka University,, Osaka,, Japan

    Shinji Shimojo

Authors
  1. Yuko Mizuno-Matsumoto
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  2. Masatsugu Ishijima
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  3. Kazuhiro Shinosaki
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  4. Takashi Nishikawa
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  5. Satoshi Ukai
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  6. Yoshitaka Ikejiri
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  7. Yoshitsugu Nakagawa
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  8. Ryouhei Ishii
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  9. Hiromasa Tokunaga
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  10. Shinichi Tamura
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  11. Susumu Date
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  12. Tsuyoshi Inouye
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  13. Shinji Shimojo
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  14. Masatoshi Takeda
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Mizuno-Matsumoto, Y., Ishijima, M., Shinosaki, K. et al. Transient Global Amnesia (TGA) in an MEG Study. Brain Topogr 13, 269–274 (2001). https://doi.org/10.1023/A:1011176612377

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  • DOI: https://doi.org/10.1023/A:1011176612377

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