Abstract
In previous studies, the highest frequencies (16%) of the CCR5 Δ32 deletion have been found in populations of Finno-Ugric origin. We here report a high CCR5 Δ32 frequency (15%) in another Finno-Ugric populations, the Estonians. The highest frequency (18%) was found on the geographically isolated Estonian island of Dagö. We examined 504 healthy unrelated individuals of Estonian nationality, whose grandparents were born in Estonia. The polymerase chain reaction assay was performed and the amplified products were digested with EcoRI.
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Kalev, I., Mikelsaar, AV., Beckman, L. et al. High frequency of the HIV-1 protective CCR5 Δ32 deletion in native Estonians. Eur J Epidemiol 16, 1107–1109 (2000). https://doi.org/10.1023/A:1010829816334
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DOI: https://doi.org/10.1023/A:1010829816334