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Possibilities of transesophageal MRI for assessment of aortic disease: A review

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Abstract

The thoracic aortic wall is a common site of atherosclerotic plaque in humans. Tools for serial, non-invasive assessment of these plaques are of value for addressing gaps in our basic understanding of the biology of plaque rupture and its relationship to atherosclerotic disease progression as well as for monitoring response to anti-atherosclerotic interventions in therapeutic clinical trials. Common approaches to assessment of the wall of the thoracic aorta in vivo are limited. Here we discuss some of the challenges and limitations encountered by conventional techniques and review a novel approach, transesophageal MRI (TEMRI). Initial experiences in applying the TEMRI approach to assessment of aortic morphology and pathology are discussed.

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References

  1. Shunk KA, Lima JAC, Heldman AW, Atalar E. Transesophageal magnetic resonance imaging. Magn Reson Med 1999; 41: 722-726.

    Google Scholar 

  2. Shunk KA, Atalar E, Rochitte C, Lima JAC. Transesophageal magnetic resonance imaging of patients with aortic atherosclerosis. Circulation (suppl.) 1999; 100(18): 1-24.

    Google Scholar 

  3. Shunk KA, Lima JAC, Rochitte C, Atalar E. Transesophageal MRI of thoracic aorta in vivo in patients with and without atherosclerosis. ISMR abstract 1999; Philadelphia.

  4. Ferrari E, Vidal R, Chevallier T, Baudouy M. Atherosclerosis of the thoracic aorta and aortic debris as a marker of poor prognosis: benefit of oral anticoagulants. J Am Coll Cardiol 1999; 33: 1317-1322.

    Google Scholar 

  5. Cohen A, Tzourio C, Bertrand B, Chauvel C, Bousser MG, Amarenco P. Aortic plaque morphology and vascular events: a follow-up study in patients with ischemic stroke. FAPS Investigators. French study of aortic plaques in stroke. Circulation 1997; 96: 3838-3841.

    Google Scholar 

  6. Fazio GP, Redberg RF, Winslow T, Schiller NB. Transesophageal echocardiographically detected atherosclerotic aortic plaque is a marker for coronary artery disease. J Am Coll Cardiol 1993; 21: 144-150.

    Google Scholar 

  7. Witteman JC, Kannel WB, Wolf PA, et al. Aortic calcified plaques and cardiovascular disease (the Framingham study). Am J Cardiol 1990; 66: 1060-1064.

    Google Scholar 

  8. Amarenco P, Cohen A, Tzourio C, et al. Atherosclerotic disease of the aortic arch and the risk of ischemic stroke. N Engl J Med 1994; 331: 1474-1479.

    Google Scholar 

  9. Matsumura Y, Takata J, Yabe T, Furuno T, Chikamori T, Doi YL. Atherosclerotic aortic plaque detected by transesophageal echocardiography: its significance and limitation as a marker for coronary artery disease in the elderly. Chest 1997; 112: 81-86.

    Google Scholar 

  10. Khoury Z, Gottlieb S, Stern S, Keren A. Frequency and distribution of atherosclerotic plaques in the thoracic aorta as determined by transesophageal echocardiography in patients with coronary artery disease. Am J Cardiol 1997; 79: 23-27.

    Google Scholar 

  11. Martin AJ, Ryan AK, Gotlieb AI, Henkelman RM, Foster FS. Arterial imaging: comparison of high-resolution US and MR imaging with histologic correlation. Radiographics 1997; 17: 189-202.

    Google Scholar 

  12. Libby P. Lesion versus lumen. Nature Medicine 1995; 1: 17-8.

    Google Scholar 

  13. Atalar E, Bottomley PA, Ocali O, et al. High resolution intravascular MRI and MRS using a catheter receiver coil. Magn Reson Med 1996; 36: 596-605.

    Google Scholar 

  14. Zimmermann-Paul GG, Quick HH, Vogt P, von Schulthess GK, Kling D, Debatin JF. High-resolution intravascular magnetic resonance imaging: monitoring of plaque formation in heritable hyperlipidemic rabbits. Circulation 1999; 99(8): 1054-1061.

    Google Scholar 

  15. Martin AJ, Henkelman RM. Intravascular MR imaging in a porcine animal model. Magn Reson Med 1994; 32(2): 224-229.

    Google Scholar 

  16. Ocali O, Atalar E. Intravascular magnetic resonance imaging using a loopless catheter antenna. Magn Reson Med 1997; 37: 112-118.

    Google Scholar 

  17. Correia LCL, Atalar E, Kelemen MD, Ocali O, Hutchins GM, Fleg JL, Gerstenblith G, Zerhouni EA, Lima JAC. Intravascular magnetic resonance imaging of aortic atherosclerotic plaque composition. Arterioscler Thromb Vasc Biol 1997; 17: 3626-3632.

    Google Scholar 

  18. Schnall MD, Lenkinski RE, Pollack HM, Imai Y, Kressel HY. Prostate: MR imaging with an endorectal surface coil. Radiology 1989; 172: 570-574.

    Google Scholar 

  19. Narayan P, Vigneron DB, Jajodia P, et al. Transrectal probe for 1H and 31P MR spectroscopy of the prostate gland. Magn Reson Med 1989; 11: 209-220.

    Google Scholar 

  20. Siegelman ES, Outwater EK, Banner MP, Ramchandani P, Anderson TL, Schnall MD. High-resolution MR imaging of the vagina. Radiographics 1997; 17: 1183-1203.

    Google Scholar 

  21. Martin AJ, McLoughlin RL, Chu KC, Barberi EA, Rutt BK. An expandable intravenous RF coil for arterial wall imaging. J Magn Reson Imaging 1998; 8: 226-234.

    Google Scholar 

  22. Montgomery DH, Ververis JJ, McGorisk G, Frohwein S, Martin RP, Taylor WR. Natural History of severe atheromatous disease of the thoracic aorta: a transesophageal echocardiographic study. J Am Coll Cardiol 1996; 27: 95-101.

    Google Scholar 

  23. Tomochika Y, Okuda F, Wasaki Y, et al. Improvement of atherosclerosis and stiffness of the thoracic descending aorta with cholesterol-lowering therapies in familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 1996; 16: 955-962.

    Google Scholar 

  24. Yuan C, Petty C, O'Brien KD, Hatsukami TS, Eary JF, Brown BG. In vitro and in situ magnetic resonance imaging signal features of atherosclerotic plaque-associated lipids. Arterioscler Thromb Vasc Biol 1997; 17: 1496-1503.

    Google Scholar 

  25. Toussant JF, LaMuraglia GM, Southern JF, Fuster V, Kantor HL. Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo. Circulation 1996; 94: 932-938.

    Google Scholar 

  26. Toussant JF, Southern JF, Fuster V, Kantor HL. T2-weighted contrast for NMR characterization of human atherosclerosis. Arterioscler Thromb Vasc Biol 1995; 15: 1533-1542.

    Google Scholar 

  27. Shunk KA, Garot J, Atalar E, Lima JAC. Transesophageal magnetic resonance imaging of the aortic arch and descending thoracic aorta in patients with aortic atherosclerosis. J Am Coll Cardiol 2001; 37: 2031-2035.

    Google Scholar 

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Authors and Affiliations

  1. Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA

    Kendrick A. Shunk, Ergin Atalar & Joao A.C. Lima

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  1. Kendrick A. Shunk
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  2. Ergin Atalar
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  3. Joao A.C. Lima
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Shunk, K.A., Atalar, E. & Lima, J.A. Possibilities of transesophageal MRI for assessment of aortic disease: A review. Int J Cardiovasc Imaging 17, 179–185 (2001). https://doi.org/10.1023/A:1010667617641

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