Abstract
Starting from (+)-Δ3-carene, synthetic equivalents of the C10-C16 fragment of epothilone carbo- analogs were obtained.
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REFERENCES
Gerth, K., Bedorf, N., Hofle, G., Irschik, H., and Reichenbach, H., J. Antibiot., 1996, vol. 49, p. 560.
Hofle, G., Bedorf, N., Steinwetz, H., Schomburg, D., Gerth, K., and Reichenbach, H., Angew. Chem., Int. Ed., 1996, vol. 35, p. 1567.
Bollag, D.M., McQueney, P.A., Zhu, J., Hensens, O., Koupal, L., Liesch, J., Goetz, M., Lazarides, E., and Woods, C.M., Cancer Res., 1995, vol. 55, p. 2325.
Schiff, P.B., Fant, J., and Horwitz, S.B., Nature, 1979, vol. 277, p. 665.
Nicolaou, K.C., Dai, W.-M., and Guy, R.P., Angew. Chem., Int. Ed., 1994, vol. 33, p. 15.
Nicolaou, K.C., Hepworth, D., King, N.P., and Finlay, M.R.V., Pure Appl. Chem., 1999, vol. 71, p. 989.
Lindel, T., Jensen, P.R., Fenical, W., Long, B.H., Casazza, A.H., Carboni, J., and Fairchild, C.R., J. Am. Chem. Soc., 1977, vol. 119, p. 8744.
Ambrosio, M.D., Guerriero, A., and Pietra, F., Helv. Chim. Acta, 1987, vol. 70, p. 2019; ibid., 1988, vol. 71, p. 964.
Kennard, O. and Watson, D.J., Tetrahedron Lett., 1968, p. 2879.
Gunasekara, S.P., Gunasekara, M., and Longley, R.E., J. Org. Chem., 1990, vol. 55, p. 4912.
Kingston, D.G.I., J. Chem. Soc., Chem. Commun., 2001, p. 867.
Chou, T.-Ch., Zhang, X.-G., Harris, C.R., Kuduk, S.D., Balog, A., Savin, K.A., Bertino, J.R., and Danishefsky, S.J., Proc. Natl. Acad. Sci. USA, 1998, vol. 95, p. 15 798.
Kharisov, R.Ya., Ishmuratov, G.Yu., Yakovleva, M.P., Botsman, O.V., Muslukhov, R.R., and Tolstikov, G.A., Izv. Ross. Akad. Nauk, Ser. Khim., 1999, p. 98.
Kropp, P.J., Heckert, D.C., and Flautt, T.J., Tetrahedron, 1968, vol. 24, p. 1385.
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Akbutina, F.A., Sadretdinov, I.F., Kuznetsov, O.M. et al. Approaches to Epothilone Carboanalogs Starting from Δ3-Carene. Russian Journal of Organic Chemistry 39, 75–81 (2003). https://doi.org/10.1023/A:1023442612661
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DOI: https://doi.org/10.1023/A:1023442612661