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Synthesis of 9-R1-10-R-1,8-Dioxodecahydroacridines and Dioximes Based on Them

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3,3,6,6-Tetramethyl-9-R1-10-R-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridines were synthesized through the intermediate α-R-methylenebisenamino ketones by the condensation of 5,5-dimethyl-3-N-R-aminocyclohex-2-enones with aliphatic, aromatic, and furan aldehydes (2-propanol, phosphorus pentoxide). It was found that the degree of substitution of the heterocycle in decahydroacridinediones has an effect on the direction of their transformations during oximation.

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Authors and Affiliations

  1. Saratov State University, Saratov, Russia

    Yu. M. Shchekotikhin, Yu. A. Getmanenko, T. G. Nikolaeva & A. P. Kriven'ko

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  1. Yu. M. Shchekotikhin
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  2. Yu. A. Getmanenko
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  3. T. G. Nikolaeva
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  4. A. P. Kriven'ko
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Shchekotikhin, Y.M., Getmanenko, Y.A., Nikolaeva, T.G. et al. Synthesis of 9-R1-10-R-1,8-Dioxodecahydroacridines and Dioximes Based on Them. Chemistry of Heterocyclic Compounds 37, 1228–1233 (2001). https://doi.org/10.1023/A:1013845426393

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  • DOI: https://doi.org/10.1023/A:1013845426393

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