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Hydrolysis of [Pt(dien)H2O]2+ and [Pd(dien)H2O]2+ complexes in water

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Abstract

The hydrolysis of the [Pt(dien)H2O]2+ and [Pd(dien)H2O]2+ complexes has been investigated by potentiometry at 298 K, in 0.1 mol dm−3 aqueous NaClO4. Least-squares treatment of the data obtained indicates the formation of mononuclear and μ-hydroxo-bridged dinuclear complexes with stability constants: log β11 = −6.94 for [Pt(dien)OH]+, log β11 = −7.16 for [Pd(dien)OH]+, and also log β22 = −9.37 for [Pt2(dien)2(OH)2]2+ and log β22 = −10.56 for [Pd2(dien)2(OH)2]2+. At pH values > 5.5, formation of the dimer becomes significant for the PtII complex, and at pH > 6.5 for the PdII complex. These results have been analyzed in relation to the antitumor activity of PtII complexes.

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  1. Department of Chemistry, Faculty of Science, University of Kragujevac, P.O. Box 60, YU-34000, Kragujevac, Yugoslavia

    Živadin D. Bugarčić, Biljana V. Petrović & Ratomir Jelić

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  1. Živadin D. Bugarčić
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  2. Biljana V. Petrović
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  3. Ratomir Jelić
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Bugarčić, Ž.D., Petrović, B.V. & Jelić, R. Hydrolysis of [Pt(dien)H2O]2+ and [Pd(dien)H2O]2+ complexes in water. Transition Metal Chemistry 26, 668–671 (2001). https://doi.org/10.1023/A:1012064512961

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