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Indocyanine green angiographic findings in fellow eyes of patients with unilateral occult neovascular age-related macular degeneration

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Abstract

Purpose: To determine the role of indocyanine green angiogaphy (ICGA) in the prediction of the development of choroidal neovascularization (CNV). Methods: We reviewed the ICG angiograms of 124 patients with newly diagnosed unilateral occult CNV secondary to age-related macular degeneration (AMD) in whom the fellow eye had only drusen by biomicroscopy and fluorescein angiography. Follow-up data of at least 12 months were obtained in all eyes. Results: 113 fellow eyes had a normal ICG study, while 11 fellow eyes revealed plaque-like late hyperfluorescence. During an average follow-up time of 18.2 months exudative AMD developed in 7 of 11 eyes with late hyperfluorescence on ICGA and in 6 of 113 with a normal ICGA study. Conclusion: ICGA may help to predict which fellow eyes are at higher risk of developing future exudative changes.

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Authors and Affiliations

  1. Department of Ophthalmology III (Retina and Vitreous Surgery), University Eye Clinic, Tübingen, Germany

    Ulrike Schneider, Faik Gelisken, Werner Inhoffen & Ingrid Kreissig

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  1. Ulrike Schneider
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  2. Faik Gelisken
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  3. Werner Inhoffen
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  4. Ingrid Kreissig
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Schneider, U., Gelisken, F., Inhoffen, W. et al. Indocyanine green angiographic findings in fellow eyes of patients with unilateral occult neovascular age-related macular degeneration. Int Ophthalmol 21, 79–85 (1997). https://doi.org/10.1023/A:1005848806641

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  • DOI: https://doi.org/10.1023/A:1005848806641

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