Abstract
The infinite-dilution apparent molar volumesV o2φ for glycine, DL-alanine, DL-α-amino-n-butyric acid, DL-valine, DL-leucine, and L-serine in 6 mol-kg−1 aqueous guanidine hydrochloride were determined at 5, 15, 25, and 35°C from precise density measurements. Using these data, the standard volumes of transfer, Δt V°, from water to 6m> aqueous guanidine hydrochloride solution were calculated. A linear relationship was found between V o2φ and temperature. Both V o2φ and Δt V° vary linearly with increasing number of carbon atoms in the alkyl chain of the amino acids. The results show that the apparent molar volumes at infinite dilution for (NH +3 ,COO-) groups increase with increasing temperature and those for CH2 and the other alkyl chains are almost constant. These results also shows that guanidine hydrochloride has stronger interactions with amino acids than urea. These phenomena are discussed in terms of the cosphere overlap model.
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Yan, Z., Wang, J., Zheng, H. et al. Volumetric Properties of Some α-Amino Acids in Aqueous Guanidine Hydrochloride at 5, 15, 25, and 35°C. Journal of Solution Chemistry 27, 473–483 (1998). https://doi.org/10.1023/A:1022608906767
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DOI: https://doi.org/10.1023/A:1022608906767