Abstract
Combining commercially available Polyglactin 910 (Vicryl®) sutures with bioactive glass powder offers new possibilities for application of composite materials in tissue engineering. Commercial bioactive glass (45S5 Bioglass®) powder was used to coat Vicryl® sutures and the tensile strength of the sutures was tested before and after immersion in simulated body fluid (SBF) as a means to assess the effect of the bioactive glass coating on suture degradation. Different gauge lengths (126.6 and 111.6 mm) and strain rates (2.54, 11.4 and 25.4 mm/min) were tested. The tensile strength of composite sutures was slightly lower than that of as-received Vicryl® sutures (404 MPa versus 463 MPa). However after 28 days immersion in SBF the residual tensile strength of the coated sutures was significantly higher, indicating a protective function of the Bioglass® coating. The tensile strength results were similar for the different gauge lengths and strain rates investigated. A qualitative explanation for the effect of bioactive glass coating on polymer degradation is offered.
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Stamboulis, A., Hench, L.L. & Boccaccini, A.R. Mechanical properties of biodegradable polymer sutures coated with bioactive glass. Journal of Materials Science: Materials in Medicine 13, 843–848 (2002). https://doi.org/10.1023/A:1016544211478
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DOI: https://doi.org/10.1023/A:1016544211478