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Surface treatments and roughness properties of Ti-based biomaterials

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Abstract

Nowadays, the use of implanted devices is a well-acknowledged practice in the field of orthopaedic and dental surgery. Scientific research and clinical experience suggest that the successful exploitation of these devices mainly depends on osseointegration, considered as both anatomical congruency and load-bearing capacity. Indeed, the osseointegration process is influenced by a wide range of factors: anatomical location, implant size and design, surgical procedure, loading effects, biological fluids, age and sex, and, in particular, surface characteristics. For this reason, several attempts have been aimed at modifying implant surface composition and morphology to optimise implant-to-bone contact and improve integration. Preliminary interactions between implanted materials and biological environment are deemed to be governed by the surface properties; they control the amount and quality of cell adhesion on the surface and, consequently, cell/tissue growth. Thus, surface properties govern new bone tissue formation and implant osseointegration. This paper reviews the state of art in the field of physical, chemical and biochemical treatments commonly used on Ti-based biomaterials for the production of biomedical devices. In particular, roughness characteristics due to physical and chemical techniques are investigated; the development of biologically active surfaces by means of biochemical functionalisation is also considered.

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References

  1. P. A. RAMIRES, A. GIUFFRIDA and E. MILELLA, Biomaterials 23 (2002) 397.

    Google Scholar 

  2. B. KASEMO and J. GOLD, Adv. Dent. Res. 13 (1999) 8.

    Google Scholar 

  3. D. A. PULEO and A. NANCI, Biomaterials 20 (1999) 2311.

    Google Scholar 

  4. B. D. BOYAN, T. W. HUMMERT, D. D. DEAN and Z. SCHWARTZ, ibid. 17 (1996) 137.

    Google Scholar 

  5. E. HEALY, C. H. THOMAS, A. REZANIA, J. E. KIM, P. J. MCKEOWN, B. LOM and P. E. HOCKBERGER, ibid. 17 (1996) 195.

    Google Scholar 

  6. S. NISHIGUCHI, H. KATO, M. NEO, M. OKA, H.-M. KIM, T. KOKUBO and T. NAKAMURA, J. Biomed. Mater. Res. 54 (2001) 198.

    Google Scholar 

  7. K. ANSELME, Biomaterials 21 (2000) 667.

    Google Scholar 

  8. A. HUNTER, C. W. ARCHER, P. S. WALKER and G. W. BLUNN, ibid. 16 (1995) 287.

    Google Scholar 

  9. J. B. BRUNSKI, Adv. Dent. Res. 13 (1999) 99.

    Google Scholar 

  10. B. BRUNSKI, Int. J. Oral. Maxillofac. Implants 3 (1998) 85.

    Google Scholar 

  11. M. TAKUMA, S. TSUTSUMI, H. TSUKAMOTO, Y. KIMURA, S. FUKUNGA, S. MIAYAUCHI and T. MARUYAMA, J. Osaka Univ. Dent. School 30 (1990) 86.

    Google Scholar 

  12. S. HANSSON, Clin. Oral. Impl. Res. 10 (1999) 394.

    Google Scholar 

  13. D. E. MACDONALD, B. MARKOVIC, A. L. BOSKEY and P. SOMASUNDARAN, Colloids Surf 11 (1998) 131.

    Google Scholar 

  14. K. ANSELME, P. LINEZ, M. BIGERELLE, D. LE MAGUER, A. LE MAGUER, P. HARDOUIN, H. F. HILDEBRAND, A. IOST and J. M. LEROY, Biomaterials 21 (2000) 1567.

    Google Scholar 

  15. C. LARSSON, P. THOMSEN, B.-O. ARONSSON, M. RODHAL, J. LAUSMAA, B. KASEMO and L. E. ERICSON, ibid. 17 (1996) 605.

    Google Scholar 

  16. D. L. COCHRAN, R. K. SCHENK, A. LUSSI, F. HIGGINBOTTOM and D. BUSER, J Biomed. Mater. Res. 40 (1998) 1.

    Google Scholar 

  17. M. BIGERELLE, K. ANSELME, B. NOËL, I. RUDERMAN, P. HARDOUIN and A. IOST, Biomaterials 23 (2002) 1563.

    Google Scholar 

  18. M. TABORELLI, P. JOBIN, P. FRANCçOIS, M. VAUDAUX, M. TONETTI, S. SZMUCKLER-MONCLER, J. P. SIMPSON and P. DESCOUTS, Clin. Oral. Impl. Res. 8 (1997) 208.

    Google Scholar 

  19. P. FRANÇOIS, P. VAUDAUX, M. TABORELLI, M. TONETTI, D. P. LEW and P. DESCOUTS, ibid. 8 (1997) 217.

    Google Scholar 

  20. J. LINCKS, B. D. BOYAN, C. R. BLANCHARD, C. H. LOHMANN, Y. LIU, D. L. COCHRAN, D. D. DEAN and Z. SCHWARTZ, Biomaterials 19 (1998) 2219.

    Google Scholar 

  21. R. CASTELLANI, J. E. DE RUIJTER, H. RENGGLI and J. A. JANSEN, Clin. Oral. Impl. Res. 10 (1999) 369.

    Google Scholar 

  22. A. KAPANEN, A. DANILOV, P. LEHENKARI, J. RYHÄNEN, T. JÄMSÄ and J. TUUKKANEN, Biomaterials 23 (2002) 3733.

    Google Scholar 

  23. K. MUSTAFA, A. WENNERBERG, J. WROBLEWSKI, K. HULTENBY, B. SILVA LOPEZ and K. ARVIDSON, Clin. Oral. Impl. Res. 12 (2001) 515.

    Google Scholar 

  24. C. APARICIO, F. J. GIL, C. FONSECA, M. BARBOSA and J. A. PLANELL, Biomaterials 24 (2003) 263.

    Google Scholar 

  25. A. WENNERBERG, T. ALBREKTSSON, B. ANDERSSON and J. J. KROL Clin. Oral. Impl. Res. 6 (1995) 24.

    Google Scholar 

  26. A. WENNERBERG, T. ALBREKTSSON, H. ULRICH and J. J. KROL, J Biomed. Eng. 14 (1992) 412.

    Google Scholar 

  27. A. WENNERBERG, T. ALBREKTSSON, C. JOHANSSON and B. ANDERSSON, Biomaterials 17 (1996) 15.

    Google Scholar 

  28. K. GOTFREDSEN, A. WENNERBERG, C. JOHANSSON, L. T. SKOVGAARD and E. HJORTING-HANSEN, J Biomed. Mater. Res. 29 (1995) 1223.

    Google Scholar 

  29. D. BUSER, R. K. SCHENK, S. STEINEMANN, J. P. FIORELLINI, C. H. FOX and H. STICH, ibid. 25 (1991) 889.

    Google Scholar 

  30. A. WENNERBERG, T. ALBREKTSSON and B. ANDERSSON, Int. J. Oral. Maxillofac. Impl. 11 (1996) 38.

    Google Scholar 

  31. A. WENNERBERG, C. HALLGREN, C. JOHANSSON and S. DANELLI, Clin. Oral. Impl. Res. 9 (1998) 11.

    Google Scholar 

  32. K.J. STOUT, E. J. DAVIES, P. J. SULLIVAN, W. P. DONG, E. MAINSAH, N. LUO, T. MATHIA and H. ZAHOUANI, (1993) The development of methods for the characterisation of roughness in three dimension, Commission of the European Communities, EUR 15178 EN, University of Birmingham.

  33. K. MUSTAFA, B. SILVA LOPEZ, K. HULTENBY, A. WENNERBERG and K. ARVIDSON, Clin. Oral. Impl. Res. 9 (1998) 195.

    Google Scholar 

  34. M. WONG, J. EULENBERGER, R. SCHENK and E. HUNZIKER, J. Biomed. Mater. Res. 29 (1995) 1567.

    Google Scholar 

  35. D. LI, S. J. FERGUSON, T. BEUTLER, D. L. COCHRAN, C. SITTIG, H. P. HIRT and D. BUSER, ibid. 60 (2002) 325.

    Google Scholar 

  36. J. Y. MARTIN, Z. SCHWARTZ, T. W. HUMMERT, D. M. SCHRAUB, J. SIMPSON, J. LANCKFORD JR., D. D. DEAN, D. L. COCHRAN and B. D. BOYAN, J Biomed. Mater. Res. 29 (1995) 389.

    Google Scholar 

  37. D. PERRIN, S. SZMUCKLER-MONCLER, C. ECHIKOU, P. POINTAIRE and J. P. BERNARD, Clin. Oral. Impl. Res. 13 (2002) 465.

    Google Scholar 

  38. P. R. KLOKKEVOLD, P. JOHNSON, S. DADGOSTARI, A. CAPUTO, J. E. DAVIES and R. D. NISHIMURA, ibid. 12 (2001) 350.

    Google Scholar 

  39. I. ABRAHAMSSON, N. U. ZITZMANN, T. BERGLUNDH, E. LINDER, A. WENNERBERG and J. LINDHE, J Clin. Periodontol. 29 (2002) 448.

    Google Scholar 

  40. T. ALBREKTSSON, P.I. BRÅNEMARK, H. A. HANSSON and J. LINDSTROM, Acta. Orthop. Scand. 52 (1981) 155.

    Google Scholar 

  41. R. ADELL, B. ERICSSON, U. LEKHOLM, P. I. BRÅNEMARK and T. JEMT, Int. J. Oral. Maxillofac. Impl. 5 (1990) 347.

    Google Scholar 

  42. A. GORANSSON, E. JANSSON, P. TENGVALL and A. WENNERBERG, Biomaterials 24 (2003) 197.

    Google Scholar 

  43. E. JANSSON and P. TENGVALL, ibid. 22 (2001) 1803.

    Google Scholar 

  44. E. JANSSON, M. KAHLTORP, P. THOMSEN and P. TENGVALL, ibid. 23 (2002) 2803.

    Google Scholar 

  45. A. WENNERBERG and T. ALBREKTSSON, Int. J Oral. Maxillofac. Impl. 15 (2000) 331.

    Google Scholar 

  46. B. W. CALLEN, R. N. SODHI and K. GRIFFITHS, Prog. Suif. Sci. 50 (1995) 269.

    Google Scholar 

  47. H. C. AMSTUTZ, P. CAMPBELL, H. MCKELLOP, T. P. SCHMALZREID, W. J. GILLESPIE, D. HOWIE, J. JACOBS, J. MEDLEY and K. MERRITT, Clin. Orthop. 329 (1996) 297.

    Google Scholar 

  48. J. J. JACOBS, A. K. SKIPOR, J. BLACK, R. URBAN and J. O. GALANTE, J Bone Joint. Surg. 73 (1991) 1475.

    Google Scholar 

  49. H. LIAO, T. WURTZ and J. LI, J. Biomed. Mater. Res. 47 (1999) 220.

    Google Scholar 

  50. C.-H. KU, D. P. PIOLETTI, M. BROWNE and P. J. GREGSON, Biomaterials 23 (2002) 1447.

    Google Scholar 

  51. M. BROWNE and P. J. GREGSON, ibid. 15 (1994) 894.

    Google Scholar 

  52. M. BROWNE, P. J. GREGSON and R. H. WEST, J. Mater. Sci.: Mater. Med. 7 (1996) 323.

    Google Scholar 

  53. J. HALL and J. LAUSMAA, Appl. Osseointegr. Res. 1 (2000) 5.

    Google Scholar 

  54. Y.-T. SUL, C. B. JOHANSSON, Y. JEONG and T. ALBREKTSSON, Med. Eng. Phys. 23 (2001) 329.

    Google Scholar 

  55. P. THOMAS and C. COOK, J. Biomed. Mater. Res. 19 (1985) 875.

    Google Scholar 

  56. L. CARLSSON, T. ROSTLUND, B. ALBREKTSSON and T. ALBREKTSSON, Int. J Oral. Maxillofac. Impl. 3 (1988) 21.

    Google Scholar 

  57. K. GOTFREDSEN, L. NIMB, E. HJORTING-HANSEN, J. S. JENSEN and A. HOLMÉN, Clin. Oral. Impl. Res. 3 (1992) 77.

    Google Scholar 

  58. J. A. JANSEN, J. G. C. WOLKE, S. SWANN, J. P. C. M. VAN DER WAERDEN and K. DE GROOT, ibid. 74 (1991) 28.

    Google Scholar 

  59. J. G. C. WOLKE, K. VAN DIJK, H. G. SCHAEKEN, K. DE GROOT and J. A. JANSEN, J Biomed. Mater. Res. 28 (1994) 1477.

    Google Scholar 

  60. J. E. G. HULSHOFF, K. VAN DIJK, J. P. C. M. VAN DER WAERDEN, J. G. C. WOLKE, L. A. GINSEL and J. A. JANSEN, ibid. 29 (1995) 967.

    Google Scholar 

  61. K. VAN DIJK, C. H. M. MARÉE, J. VERHOEVEN, F. H. P. M. HABRAKEN and J. A. JANSEN, ibid. 41 (1998) 41.

    Google Scholar 

  62. S. VERCAIGNE, J. G. C. WOLKE, I. NAERT and J. A. JANSEN, Clin. Oral. Impl. Res. 11 (2000) 305.

    Google Scholar 

  63. L. CLAES, P. HUTZSCHENREUTER and O. POHLER, Archiv für Orthopdilische und Unfallchirurgie 85 (1976) 155.

    Google Scholar 

  64. K. DE GROOT, R. G. T. GEESINK, C. P. A. T. KLEIN and P. SEREKIAN, J Biomed. Mater. Res. 21 (1987) 1375.

    Google Scholar 

  65. T. ALBREKTSSON and C. JOHANSSON, (1991) in “The Bone-Biomaterial Interface”, edited by J. E. Davies (University of Toronto Press) p. 357.

  66. K. SUZUKI, K. AOKI and K. OHYA, Bone 21 (1997), 507.

    Google Scholar 

  67. S. J. LEE, Yonsei Med. J. 41 (2000) 704.

    Google Scholar 

  68. T. SAKOU, Bone 22 (1998) 591.

    Google Scholar 

  69. K. BESSHO, D. L. CARNES, R. CAVIN, H.-Y. CHEN and J. L. ONG, Clin. Oral. Impl. Res. 10 (1999) 212.

    Google Scholar 

  70. Y. SUZUKI, M. TANIHARA, K. SUZUKI, A. SAITOU, W. SUFAN and Y. NISHIMURA, J Biomed. Mater. Res. 50 (2000) 405.

    Google Scholar 

  71. G. SCHMIDMAIER, B. WILDEMANN, H. BAIL, M. LUCKE, T. FUCHS, A. STEMBERGER, A. FLYVBJERG, N. P. HAAS and M. RASCHKE, Bone 28 (2001) 341.

    Google Scholar 

  72. K. C. DEE, D. C. RUEGER, T. T. ANDERSEN and R. BIZIOS, Biomaterials 17 (1996) 209.

    Google Scholar 

  73. K. C. DEE, T. T. ANDERSEN and R. BIZIOS, J. Biomed. Mater. Res. 40 (1998) 371.

    Google Scholar 

  74. M. DETTIN, M. T. CONCONI, R. GAMBARETTO, A. PASQUATO, M. FOLIN, C. DI BELLO and P. P. PARNIGOTTO, ibid. 60 (2002) 466.

    Google Scholar 

  75. A. NANCI, J. D. WEST, L. PERU, P. BRUNET, V. SHARMA, S. ZALZAL and M. D. MCKEE, ibid. 40 (1998) 324.

    Google Scholar 

  76. D. A. PULEO, Biomaterials 17 (1996) 217.

    Google Scholar 

  77. K. E. HEALY, A. REZANIA and R. A. STILE, Ann. N. Y. Acad. Sci. 875 (1999) 24.

    Google Scholar 

  78. D. A. PULEO, R. A. KISSILING and M.-S. SHEU, Biomaterials 23 (2002) 2079.

    Google Scholar 

  79. D. M. FERRIS, G. D. MOODIE, P. M. DIMOND, C. W. D. GIORANNI, M. G. EHRLICH and R. F. VALENTINI, ibid. 20 (1999) 2323.

    Google Scholar 

  80. A. REZANIA and K. E. HEALY, J. Biomed. Mater. Res. 52 (2000) 595.

    Google Scholar 

  81. J. D. HECKMAN, W. EHLER, B. P. BROOKES, T. B. AUFDEMORTE, C. H. LOHMANN, T. MORGAN and B. D. BOYAN, J Bone Joint. Surg. 81 (1999) 1717.

    Google Scholar 

  82. C. M. AGRAWAL, A. PENNICK, X. WANG and R. C. SCHENK, J Biomed. Mater. Res. 36 (1997) 516.

    Google Scholar 

  83. J. R. GLASS, K. T. DICKERSON, K. STECKER and J. W. POLAREK, Biomaterials 17 (1996) 1101.

    Google Scholar 

  84. E. DE GIGLIO, L. SABBATINI, S. COLUCCI and G. ZAMBONINI, J Biomater. Sci. Poly. Edn. 11 (2000) 1073.

    Google Scholar 

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Bagno, A., Di Bello, C. Surface treatments and roughness properties of Ti-based biomaterials. Journal of Materials Science: Materials in Medicine 15, 935–949 (2004). https://doi.org/10.1023/B:JMSM.0000042679.28493.7f

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