Abstract
The complexation processes between the calcium channel antagonist drug nifedipine (Nif) and CuII lead to the formation of a mononuclear violet complex CuNif2Cl2 (1). Monocrystals of (1) were isolated and their structure determined by X-ray diffraction. Copper is coordinated through N of the NH group of the ligand. The metal ion is coordinated also with two Cl− anions and the geometry of the CuN2Cl2 core is a near flat square. The magnetic and optical properties of (1) were also studied using electronic and i.r. spectra, e.p.r. and magnetochemical measurements.
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Bontchev, P.R., Mehandjiev, D.R., Ivanova, B.B. et al. A mononuclear complex of copper(II) with a calcium channel antagonist nifedipine. Synthesis, properties, crystal structure. Transition Metal Chemistry 28, 745–748 (2003). https://doi.org/10.1023/A:1026061029474
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DOI: https://doi.org/10.1023/A:1026061029474