Department of Synthetic Chemistry and Biological Chemistry, Graduate School of
Engineering, Kyoto University, Kyoto 615-8510, Japan, and Research Center for
Materials Science, Nagoya University, Nagoya 464-8602, Japan
A novel three-component cyclization using allenylboronate ester is described. A three-component assembly of allenylboronate ester, aryl
iodides, and stabilized carbon nucleophiles took place in the presence of palladium catalyst, furnishing functionalized alkenylboronate esters
with high regio- and stereoselectivity. A Rh-catalyzed cyclization of the resultant three-component products then afforded interesting carbocyclic
frameworks efficiently.
and
