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Molecular genetic mechanisms of teratozoospermia

Published online by Cambridge University Press:  06 February 2023

Ying Chang Open the ORCID record for Ying Chang [Opens in a new window] ,
Xin Jiang ,
Wei Liu ,
Dongfang Zhang ,
Shubao Yang  and
Donghai Zhao
Ying Chang
Affiliation:
Jilin Medical University, jilin, 132013, China
Xin Jiang
Affiliation:
Jilin Medical University, jilin, 132013, China
Wei Liu
Affiliation:
Jilin Medical University, jilin, 132013, China
Dongfang Zhang
Affiliation:
Jilin Medical University, jilin, 132013, China
Shubao Yang*
Affiliation:
Jilin Medical University, jilin, 132013, China
Donghai Zhao*
Affiliation:
Jilin Medical University, jilin, 132013, China
*
Authors for correspondence: Donghai Zhao, Jilin Medical University, jilin, 132013, China. E-mail: zdh751027@126.com; Shubao Yang, Jilin Medical University, jilin, 132013, China. E-mail: 18721325@qq.com
Authors for correspondence: Donghai Zhao, Jilin Medical University, jilin, 132013, China. E-mail: zdh751027@126.com; Shubao Yang, Jilin Medical University, jilin, 132013, China. E-mail: 18721325@qq.com
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Summary

In recent years, the incidence of teratospermia has been increasing, and it has become a very important factor leading to male infertility. The research on the molecular mechanism of teratospermia is also progressing rapidly. This article briefly summarizes the clinical incidence of teratozoospermia, and makes a retrospective summary of related studies reported in recent years. Specifically discussing the relationship between gene status and spermatozoa, the review aims to provide the basis for the genetic diagnosis and gene therapy of teratozoospermia.

Keywords

GeneMale infertilitySpermatogenesisTeratozoospermia
Type
Review Article
Information
Zygote , Volume 31 , Issue 2 , April 2023 , pp. 101 - 110
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Copyright
© The Author(s), 2023. Published by Cambridge University Press

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Footnotes

a

These authors contributed equally to this work.

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