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The generation of aerosols by accidents which may occur during plant-scale production of micro-organisms

Published online by Cambridge University Press:  19 October 2009

J. Ashcroft
Affiliation:
Chemical Defence Establishment, Porton, Salisbury, Wilts, U.K.
N. P. Pomeroy
Affiliation:
Chemical Defence Establishment, Porton, Salisbury, Wilts, U.K.
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Summary

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Experiments have been performed to simulate accidents which may occur during large-scale production of micro-organisms. Four types of accident, which were considered to be the most likely to result in the greatest hazard to health, were simulated using a bacterial model. The accidents were all concerned with faults occurring in the operation of the microbial fermenter. Gross contamination of surfaces occurred in all experiments, but only three types of accident produced a measurable aerosol.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1983

References

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