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The minimum effective dose of praziquantel in treatment of Hymenolepis diminuta in rats

Published online by Cambridge University Press:  05 June 2009

P.C. Fan  and
A. Ito
P.C. Fan
Affiliation:
Department of Parasitology, National Yangming Medical College, Taipei, Taiwan, Republic of China
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu City, Japan
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Abstract

To determine the minimum effective dose of praziquantel against Hymenolepis diminuta in rats, 5.0 mg/kg, 2.5 mg/kg, 1.0 mg/kg, 0.5 mg/kg, 0.1 mg/kg, or 0.05 mg/kg praziquantel were given to each of five experimentally infected rats in six groups. Faecal samples from each rat were examined for worms on day 10. Based on the results of faecal examination and autopsy, the minimum effective dose of praziquantel against Hymenolepis diminuta in rats was determined to be 0.5 mg/kg.

Type
Research Note
Information
Journal of Helminthology , Volume 69 , Issue 1 , March 1995 , pp. 91 - 92
Copyright
Copyright © Cambridge University Press 1995

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