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Tpi-1 and Gapd are linked very closely on mouse chromosome 6

Published online by Cambridge University Press:  14 April 2009

Walter Pretsch*
Affiliation:
GSF-Institut für Säugetiergenetik, Ingolstädter Landstr. 1, D-8042 Neuherberg, Federal Republic of Germany
Angelika Neuhäuser-Klaus
Affiliation:
GSF-Institut für Säugetiergenetik, Ingolstädter Landstr. 1, D-8042 Neuherberg, Federal Republic of Germany
Siegbert Merkle
Affiliation:
GSF-Institut für Säugetiergenetik, Ingolstädter Landstr. 1, D-8042 Neuherberg, Federal Republic of Germany
*
* Corresponding author.

Summary

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Mutations in the structural genes for triosephosphate isomerase and glyceraldehyde-3-phosphate dehydrogenase activity in the mouse, selected after mutagen treatment, were used to estimate the map distance between the two loci. It is shown that Tpi-1 and Gapd are closely linked on chromosome 6, with a recombination frequency of 0·1±0·1%.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1991

References

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