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A new spontaneous mutation at the tufted locus within a mouse t haplotype

Published online by Cambridge University Press:  14 April 2009

Lee M. Silver ,
Lois Cisek ,
Catherine Jackson  and
Deborah Lukralle
Lee M. Silver
Affiliation:
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, U.S.A.
Lois Cisek
Affiliation:
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, U.S.A.
Catherine Jackson
Affiliation:
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, U.S.A.
Deborah Lukralle
Affiliation:
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, U.S.A.

Summary

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We report here the occurrence of a new spontaneous mutation at the tufted locus present within the crossover-suppressed region of the complete t haplotype fwLub1 This new tufted allele shows complete expressivity of the tufted phenotype without any apparent effect on viability or reproduction. The presence of a tufted mutation within a t haplotype that is cytologically marked by a Robertsonian translocation is particularly useful in genetic experiments aimed at understanding the structure and function of t haplotypes.

Type
Short Paper
Information
Genetics Research , Volume 45 , Issue 1 , February 1985 , pp. 107 - 112
Copyright
Copyright © Cambridge University Press 1985

References

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